Zusammengefasst gesagt basiert die Doman Therapie auf der Theorie das nicht beschädigte Bereiche des Gehirns durch intensive Reizzuführung von außen so "programmiert" werden können um die Funktionen der beschädigten Bereiche des Gehirns zu übernehmen.

The recapitulation theory it is built upon has been discarded by the natural sciences.
The suggestion that motor development has stages, which depend on earlier developments, is not supported by evidence.
There is no evidence that passive movements by a child, forced to engage in crawling movements, affects neurological organization.
Children who voluntarily perform an activity (such as sitting or walking) before mastering preceding stages, are prevented from doing so by the IAHP—possibly harming the child.
The only scientific paper published by Doman on patterning (in 1960) contains many methodological errors and overstatements of findings. The study had no control group so was unable to compare with children who would naturally show some developmental progress over time. When independent scientists compared the results with the progress made by untreated children, the "results of patterning appear singularly unimpressive".
The patterning procedure may be harmful to its participants (the parents experience guilt at being unable to achieve the intensive program required) and other family members through neglect.
It is cruel to offer hope through a program that is impossible to fully carry out.

[...]

Kathleen Ann Quill, in her book Teaching children with autism: What parents want,[38] says "thousands of families have wasted time and money to follow Doman's methods." She goes on to say "Professionals have nothing to learn from Doman's pseudoscientific treatments, but they have plenty to learn from his marketing strategy", which is aimed at parent's "hopes and fantasies".